Article
miRNAs affect the development of hepatocellular carcinoma via dysregulation of their biogenesis and expression.
Cell communication and signaling : CCS - 11 Jul 2014
Chu Rui, Mo Guangquan, Duan Zhijun, Huang Mei, Chang Jiuyang, Li Xiaodong, Liu Pixu
Abstract excerpt
The pathogenesis of hepatocellular carcinoma (HCC) is not fully understood, which has affected the early diagnosis and treatment of HCC and the survival time of patients. MicroRNAs (miRNAs) are a class of evolutionarily conserved small, non-coding RNAs, which regulate the expression of various genes post-transcriptionally. Emerging evidence indicates that the key enzymes involved in the miRNA biosynthesis pathway...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.