<span class="word">Cytochrome <span class="word">P450 <span class="word">in <span class="word"><span class="changedDisabled">Cirrhosis

Abstract excerpt

A specific key point in liver cirrhosis is the decreased metabolic capacity for drugs. So medicines which are metabolized by oxidative biotransformation play a great role in liver pathology. Responsible for the drug metabolism that takes place in liver during illnes, are three cytochrome P450 (P450 or CYP) gene families in liver microsomes (CYP 1, CYP2 and CYP3). In attention of various studies, is cytochrome P450...

Topics

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• Cholecalciferol
• Cytochrome P-450 Enzyme System
• Drug-Induced Hepatotoxicity and Protection
• Drug Transport and Resistance Mechanisms
• Metabolic Diseases
• Mutation
• Pharmacogenetics and Drug Metabolism
• Steroids

Identifiers and source

Literature Corpus work

021c5009-c389-562f-ba3d-4057f62d5339

DOI

10.20944/preprints202501.0281.v2