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Article

Profiling variable-number tandem repeat variation across populations using repeat-pangenome graphs.

Nature communications - 12 Jul 2021

Lu Tsung-Yu, Chaisson Mark J P

Abstract excerpt

Variable number tandem repeats (VNTRs) are composed of consecutive repetitive DNA with hypervariable repeat count and composition. They include protein coding sequences and associations with clinical disorders. It has been difficult to incorporate VNTR analysis in disease studies that use short-read sequencing because the traditional approach of mapping to the human reference is less effective for repetitive and...

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Identifiers

PMID: 34253730
DOI: 10.1038/s41467-021-24378-0
PMCID: PMC8275641

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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