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Recent zoonotic spillover and tropism shift of a Canine Coronavirus is associated with relaxed selection and putative loss of function in NTD subdomain of spike protein

2021-11-17

Abstract excerpt

<h4>ABSTRACT</h4> A recent study reported the occurrence of Canine Coronavirus (CCoV) in nasopharyngeal swabs from a small number of patients hospitalized with pneumonia during a 2017-18 period in Sarawak, Malaysia. Because the genome sequence for one of these isolates is available, we conducted comparative evolutionary analyses of the spike gene of this strain (CCoV-HuPn-2018), with other available Alphacoronav...

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Literature Corpus work
01da48d0-f96b-5416-bca3-e78a172c2c91
DOI
10.1101/2021.11.15.468709
Open publication

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Recent zoonotic spillover and tropism shift of a Canine Coronavirus is associated with relaxed selection and putative loss of function in NTD subdomain of spike proteinDOI 10.1101/2021.11.15.468709
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