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Transcriptomic analysis identifies injury-responsive fibroblast populations as potential mediators of Wnt-dependent spinal cord regeneration

2024-05-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> In humans and other mammals, spinal cord injury (SCI) can lead to a permanent loss of sensory and motor function, due to the inability of damaged neurons and axons to regenerate. However, other vertebrate species including zebrafish exhibit complete spinal cord regeneration and functional recovery after SCI. Wnt signaling is required for neurogenesis and axon regrowth in a l...

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Literature Corpus work
0135ae9a-0885-5c11-9858-f05ae97f2343
DOI
10.1101/2024.05.17.594712
Open publication

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Transcriptomic analysis identifies injury-responsive fibroblast populations as potential mediators of Wnt-dependent spinal cord regenerationDOI 10.1101/2024.05.17.594712
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