Article

Parechovirus infection in human brain organoids: host innate inflammatory response and not neuro-infectivity correlates to neurologic disease

2023-11-02

Abstract excerpt

<title>Abstract</title> <p>Picornaviruses<italic> </italic>are a leading cause of central nervous system (CNS) infections. While genotypes such as Parechovirus A3 (PeV-A3) and echovirus 11 (E11) can elicit severe neurological disease, the highly prevalent PeV-A1 is not associated with CNS disease. Here, we expand our current understanding of these differences in PeV-A CNS disease using human brain organoids and c...

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Literature Corpus work: 0106b905-cccc-5e09-a302-2b4c2cbd4fc2
DOI: 10.21203/rs.3.rs-3545433/v1

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