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Article

Human parechovirus infection in neonates and young infants: Clinical features, diagnostic challenges, and neurodevelopmental outcomes.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jun 2026

Brisca Giacomo, Mariani Marcello, Bellini Tommaso, Tortora Domenico, Moscatelli Andrea, Castagnola Elio

Abstract excerpt

Human parechoviruses (HPeVs) are increasingly recognized as viral pathogens in neonates and young infants. Among the 18 identified genotypes, HPeV-3 is most strongly associated with severe disease during early infancy, including sepsis-like illness and central nervous system (CNS) infection. Clinical recognition can be challenging because typical laboratory features of CNS infection are frequently absent:...

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PMID: 42001594
DOI: 10.1016/j.jcv.2026.105945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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