Article

Epigenetic Regulation Mediated by Methylation in the Pathogenesis and Precision Medicine of Rheumatoid Arthritis

2020-04-15

Abstract excerpt

Rheumatoid arthritis (RA) as a complex disease is thought triggered by interaction between genetics and environment, especially the shared epitope (SE) and cell surface calreticulin (CSC) theory. However, all the evidence shows genetic diversity and environment exposure cannot explain all the clinical characteristics heterogeneity of rheumatoid arthritis. In contrast, recent studies demonstrate that epigenetics pl...

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Literature Corpus work: 00ef1bba-7dfd-56d6-beea-6367b6f05259
DOI: 10.20944/preprints202004.0237.v1

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