Article

Targeted RNA NextGenSeq profiling in oncology using single molecule molecular inversion probes

2018-10-10

Abstract excerpt

Hundreds of biology-based precision drugs are available that neutralize aberrant molecular pathways in cancer. Molecular heterogeneity and the lack of reliable companion diagnostic biomarkers for many drugs makes targeted treatment of cancer inaccurate for many individuals, leading to futile overtreatment. To acquire a comprehensive insight in aberrant actionable biological pathways in individual cancers we applie...

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Literature Corpus work: 00e51ca7-b822-5b93-b765-e2e94c6448b8
DOI: 10.1101/440065

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