Article

Profiling of small non-coding RNAs across cellular and biofluid compartments: implications for multiple sclerosis immunopathology

2020-05-16

Abstract excerpt

Multiple sclerosis (MS), a chronic inflammatory disease of the central nervous system (CNS), is associated with dysregulation of microRNAs (miRNA). We here analyzed all classes of small non-coding RNAs (sncRNAs) in matching peripheral blood mononuclear cells (PBMCs), plasma, cerebrospinal fluid (CSF) cells and cell-free CSF from relapsing-remitting (RRMS, n=12 in relapse, n=11 in remission), secondary progressive...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 00b34134-225f-5aeb-a5c9-66bf5dc95b59
DOI: 10.1101/2020.05.15.097519

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Profiling of small non-coding RNAs across cellular and biofluid compartments: implications for multiple sclerosis immunopathologyDOI 10.1101/2020.05.15.097519Read

Global exosome transcriptome profiling reveals biomarkers for multiple sclerosisSemantic proximity Read

Regulated microRNAs in the CSF of patients with multiple sclerosisSemantic proximity Read

Comprehensive analysis of microRNA profiles in multiple sclerosis including next-generation sequencingSemantic proximity Read

Comparing Single-Cell Transcriptomes of Blood and Cerebrospinal Fluid Leukocytes in Multiple SclerosisSemantic proximity Read

Next-generation sequencing reveals broad down-regulation of microRNAs in secondary progressive multiple sclerosis CD4+ T cellsSemantic proximity Read

Long Non-Coding RNAs, Novel Offenders or Guardians in Multiple Sclerosis: A Scoping Review.Semantic proximity Read

Circulating MicroRNAs as biomarkers for disease staging in multiple sclerosisSemantic proximity Read

miRNA profiling for biomarker discovery in multiple sclerosis: from microarray to deep sequencing.Semantic proximity Read

miRNA Signature in CSF From Patients With Primary Progressive Multiple SclerosisSemantic proximity Read

CSF microRNAs discriminate MS activity and share similarity to other neuroinflammatory disordersSemantic proximity Read

The role of miRNAs in multiple sclerosis pathogenesis, diagnosis, and therapeutic resistanceSemantic proximity Read

Expression Analysis of Long Non-coding RNAs in the Blood of Multiple Sclerosis PatientsSemantic proximity Read