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Article

Circulating MicroRNAs as biomarkers for disease staging in multiple sclerosis

13 Mar 2013

Abstract excerpt

OBJECTIVE: MicroRNAs (miRNAs) are single-stranded, small noncoding RNAs that regulate gene expression. Because they are stable in serum, they are being developed as biomarkers for cancer and other diseases. In multiple sclerosis (MS), miRNAs have been studied in cell populations but not in the circulation. In MS, a major challenge is to develop immune biomarkers to monitor disease. We asked whether circulating...

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PMID: 23494648
DOI: 10.1002/ana.23880

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