Article

Multi-omic analyses of a twin pair with mirror image cleft lip identifies pathogenic variant in<i>FGF20</i>modified by differential methylation upstream of<i>ZFP57</i>

2024-11-18

Abstract excerpt

<h4>Background</h4> Disturbances in the intricate processes that control craniofacial morphogenesis can result in birth defects, most common of which are orofacial clefts (OFCs). Nonsyndromic cleft lip (nsCL), one of the phenotypic forms amongst OFCs, has a non-random laterality presentation with the left side being affected twice as often compared to the right side. This study investigates the etiology of nsCL an...

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Literature Corpus work: 0093ef2e-bc83-5e72-bbe0-ac1b18afc7a2
DOI: 10.1101/2024.11.16.24317351

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