Article

Two novel lncRNAs discovered in human mitochondrial DNA using PacBio full-length transcriptome data

2016-10-06

Abstract excerpt

In this study, we introduced a general framework to use PacBio full-length transcriptome sequencing for the investigation of the fundamental problems in mitochondrial biology, e.g. genome arrangement, heteroplasmy, RNA processing and the regulation of transcription or replication. As a result, we produced the first full-length human mitochondrial transcriptome from the MCF7 cell line based on the PacBio platform...

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Literature Corpus work: 007dad3c-d3a9-5a7f-9d8a-7fed9a6f78aa
DOI: 10.1101/079517

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