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Article

The identification of markers segregating with resistance to Schistosoma mansoni infection in the snail Biomphalaria glabrata.

Proceedings of the National Academy of Sciences of the United States of America - 16 Feb 1999

Knight M, Miller A N, Patterson C N, Rowe C G, Michaels G, Carr D, Richards C S, Lewis F A

Abstract excerpt

Both snail and parasite genes determine the susceptibility of the snail Biomphalaria glabrata to infection with the trematode Schistosoma mansoni. To identify molecular markers associated with resistance to the parasite in the snail host, we performed genetic crosses between parasite-resistant and -susceptible isogenic snails. Because resistance to infection in adult snails is controlled by a single locus, DNA...

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Identifiers

PMID: 9990054
DOI: 10.1073/pnas.96.4.1510
PMCID: PMC15498

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