Article
Susceptibility of BS90 Biomphalaria glabrata snails to infection by SmLE Schistosoma mansoni segregates as a dominant allele in a cluster of polymorphic genes for single-pass transmembrane proteins.
PLoS neglected tropical diseases - 1 Sept 2024
Blouin Michael S, Bollmann Stephanie R, Le Clec'h Winka, Chevalier Frédéric D, Anderson Timothy J C, Tennessen Jacob A
Abstract excerpt
The trematodes that cause schistosomiasis in humans require aquatic snails as intermediate hosts. Identifying the genes in snails at which allelic variation controls resistance to infection by schistosomes could lead to novel ways to break the cycle of transmission. We therefore mapped genetic variation within the BS90 population of Biomphalaria glabrata snails that controls their resistance to infection by the...
Topics
- Animals
- Schistosoma mansoni
- Biomphalaria
- Alleles
- Membrane Proteins
- Polymorphism, Genetic
- Schistosomiasis mansoni
- Haplotypes