Article
Schistosoma mansoni: use of a cloned ribosomal RNA gene probe to detect restriction fragment length polymorphisms in the intermediate host Biomphalaria glabrata.
Experimental parasitology - 1 Oct 1991
Knight M, Brindley P J, Richards C S, Lewis F A
Abstract excerpt
Adult susceptibility of Biomphalaria glabrata to Schistosoma mansoni infection is controlled by simple Mendelian genetics. In this study a molecular approach was used to determine the degree of genetic variation between well-defined lines of B. glabrata which are either resistant (10-R2) or susceptible (M-line) to S. mansoni infection. A cloned probe pSM389, which contains part of the S. mansoni small ribosomal...
Topics
- Animals
- Biomphalaria
- Blotting, Southern
- Cloning, Molecular
- DNA Probes
- DNA, Ribosomal
- Deoxyribonucleases, Type II Site-Specific
- Genetic Variation
- Host-Parasite Interactions
- Polymorphism, Restriction Fragment Length