Article
Selective deletions involving the organophosphorus hydrolase gene adpB from Nocardia strain B-1.
Microbiological research - 1 Nov 1998
Mulbry W
Abstract excerpt
The organophosphorus hydrolase (OPH) of Nocardia sp. strain B-1 is capable of hydrolyzing organophosphate insecticides such as coumaphos and parathion. The 40,000 dalton OPH and the responsible gene (termed adpB) have been previously isolated and described. OPH activity in Nocardia strain B-1 is spontaneously lost at high frequency during the growth of laboratory cultures. In order to understand the genetic basis...
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