Article
An attenuated strain of Bacillus anthracis (CDC 684) has a large chromosomal inversion and altered growth kinetics.
BMC genomics - 30 Sept 2011
Okinaka Richard T, Price Erin P, Wolken Spenser R, Gruendike Jeffrey M, Chung Wai Kwan, Pearson Talima, Xie Gary, Munk Chris, Hill Karen K, Challacombe Jean, Ivins Bruce E, Schupp James M, Beckstrom-Sternberg Stephen M, Friedlander Arthur, Keim Paul
Abstract excerpt
BACKGROUND: An isolate originally labeled Bacillus megaterium CDC 684 was found to contain both pXO1 and pXO2, was non-hemolytic, sensitive to gamma-phage, and produced both the protective antigen and the poly-D-glutamic acid capsule. These phenotypes prompted Ezzell et al., (J. Clin. Microbiol. 28:223) to reclassify this isolate to Bacillus anthracis in 1990. RESULTS: We demonstrate that despite these B....
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