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Article

DNA variation in a 5-Mb region of the X chromosome and estimates of sex-specific/type-specific mutation rates.

American journal of human genetics - 1 Feb 1999

Anagnostopoulos T, Green P M, Rowley G, Lewis C M, Giannelli F

Abstract excerpt

We describe a new approach for the study of human genome variation, based on our solid-phase fluorescence chemical mismatch-cleavage method. Multiplex screening rates >/=80 kb/36-lane gels are achieved, and accuracy of mismatch location is within +/-2 bp. The density of differences between DNA from any two humans is sufficiently low, and the estimate of their position is accurate enough, to avoid sequencing of...

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Identifiers

PMID: 9973287
DOI: 10.1086/302250
PMCID: PMC1377759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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