One founder/one gene hypothesis in a new expanding population: Saguenay (Quebec, Canada).

Article

One founder/one gene hypothesis in a new expanding population: Saguenay (Quebec, Canada).

Human biology - 1 Feb 1999

Heyer E

Abstract excerpt

High frequencies of some rare inherited recessive disorders can be found in the Saguenay region of Quebec, Canada. Four disorders have a carrier frequency of about 0.04 (in the range 0.035-0.05): pseudovitamin D-dependent rickets, hereditary tyrosinemia type 1, Charlevoix-Saguenay spastic ataxia,...

Topics

Chi-Square Distribution
Female
Gene Frequency
Genes, Recessive
Genetic Diseases, Inborn
Genetic Heterogeneity
Heterozygote
Humans
Male
Models, Genetic
Mutation
Population Surveillance
Quebec

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