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Article

Gene expression of the GATA-3 transcription factor is increased in atopic asthma.

The Journal of allergy and clinical immunology - 1 Feb 1999

Nakamura Y, Ghaffar O, Olivenstein R, Taha R A, Soussi-Gounni A, Zhang D H, Ray A, Hamid Q

Abstract excerpt

BACKGROUND: High expression of IL-5 by T cells in the airways of asthmatic individuals is believed to play a fundamental role in the eosinophilia associated with this disease. Recently, the transcription factor GATA-3 was shown to be critical for IL-5 gene expression in TH2 cells in vitro. OBJECTIVE: Our aim was to examine the expression of GATA-3 mRNA and its colocalization within the airways of asthmatic and...

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Identifiers

PMID: 9949310
DOI: 10.1016/s0091-6749(99)70493-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Gene expression of the GATA-3 transcription factor is increased in atopic asthma.PMID 9949310Read ↗

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