Different tachykinin receptors mediate chloride secretion in the distal colon through activation of submucosal neurones.

doi:10.1007/pl00005327

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Article

Different tachykinin receptors mediate chloride secretion in the distal colon through activation of submucosal neurones.

Naunyn-Schmiedeberg's archives of pharmacology - 1 Jan 1999

Frieling T, Dobreva G, Weber E, Becker K, Rupprecht C, Neunlist M, Schemann M

Abstract excerpt

We investigated the role of tachykinin receptor subtypes on secretory responses in the guinea-pig distal colon using Ussing chamber experiments and intracellular recordings from submucosal neurones. Choline acetyltransferase (ChAT) and vasoactive intestinal polypeptide (VIP) were demonstrated in...

Topics

Action Potentials
Animals
Chlorides
Cholinergic Antagonists
Colon
Guinea Pigs
Immunohistochemistry
In Vitro Techniques
Intestinal Mucosa
Neurokinin-1 Receptor Antagonists
Neurons
Phenotype
Receptors, Neurokinin-1
Receptors, Neurokinin-3
Receptors, Tachykinin
Substance P
Tachykinins
Tetrodotoxin

Source

Open in PubMed

Identifiers

PMID: 9933154
DOI: 10.1007/pl00005327

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9933154-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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