Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Different tachykinin receptors mediate chloride secretion in the distal colon through activation of submucosal neurones.

Naunyn-Schmiedeberg's archives of pharmacology - 1 Jan 1999

Frieling T, Dobreva G, Weber E, Becker K, Rupprecht C, Neunlist M, Schemann M

Abstract excerpt

We investigated the role of tachykinin receptor subtypes on secretory responses in the guinea-pig distal colon using Ussing chamber experiments and intracellular recordings from submucosal neurones. Choline acetyltransferase (ChAT) and vasoactive intestinal polypeptide (VIP) were demonstrated in submucosal neurones by immunohistochemistry. In Ussing chamber experiments substance P (SP), the NK1-receptor agonist...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chlorides
Share to Colon

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Guinea Pigs

Share to Immunohistochemistry

Share to In Vitro Techniques

Share to Intestinal Mucosa

Share to Neurons

Share to Phenotype

Source

Identifiers

PMID: 9933154
DOI: 10.1007/pl00005327

Genes

VIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Different tachykinin receptors mediate chloride secretion in the distal colon through activation of submucosal neurones.PMID 9933154Read ↗

The role of mechanosensitive ion channels in the gastrointestinal tractSemantic proximity Read ↗

Plasticity and ambiguity of the electrophysiological phenotypes of enteric neurons.Semantic proximity Read ↗

Sensory signal transduction in the vagal primary afferent neurons.Semantic proximity Read ↗

Altered substance P signaling underlies perivascular sensory nerve dysfunction in inflammatory bowel diseaseSemantic proximity Read ↗

Neurochemical features of endomorphin-2-containing neurons in the submucosal plexus of the rat colon.Semantic proximity Read ↗

Neurochemical and morphological phenotypes of vagal afferent neurons innervating the adult mouse jejunum.Semantic proximity Read ↗

Defective cholinergic Cl(-) secretion and detection of K(+) secretion in rectal biopsies from cystic fibrosis patients.Semantic proximity Read ↗

Substance P and Neurokinin 1 receptor - expression is affected in the ileum of mice with mutation in the W locus.Semantic proximity Read ↗

Cloning, characterization, and functional expression of a CNP receptor regulating CFTR in the shark rectal glandSemantic proximity Read ↗

Neurochemical phenotypes of myenteric neurons in the rhesus monkey.Semantic proximity Read ↗

Effect of SNI-2011 on amylase secretion from parotid tissue in rats and in neuronal nitric oxide synthase knockout mice.Semantic proximity Read ↗

Roles of Na(+)/Ca(2+) exchanger isoforms NCX1 and NCX2 in motility in mouse ileum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.