Article
Reliable genotyping of short tandem repeat loci without an allelic ladder using time-of-flight mass spectrometry.
International journal of legal medicine - 1 Jan 1998
Butler J M, Li J, Shaler T A, Monforte J A, Becker C H
Abstract excerpt
DNA separations which traditionally have been performed by slab gel or capillary electrophoresis, may now be conducted via time-of-flight mass spectrometry (TOF-MS). The advantages of using a mass spectrometry approach for short tandem repeat (STR) characterization include a dramatic increase in both the speed of analysis and the accuracy of mass measurements. We report here typing of the STR loci TH01, TPOX, and...
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