Reliable genotyping of short tandem repeat loci without an allelic ladder using time-of-flight mass spectrometry.

doi:10.1007/s004140050197

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Article

Reliable genotyping of short tandem repeat loci without an allelic ladder using time-of-flight mass spectrometry.

International journal of legal medicine - 1 Jan 1998

Butler J M, Li J, Shaler T A, Monforte J A, Becker C H

Abstract excerpt

DNA separations which traditionally have been performed by slab gel or capillary electrophoresis, may now be conducted via time-of-flight mass spectrometry (TOF-MS). The advantages of using a mass spectrometry approach for short tandem repeat (STR) characterization include a dramatic increase in...

Topics

Alleles
Chromosome Mapping
Genotype
Humans
Mass Spectrometry
Sensitivity and Specificity
Tandem Repeat Sequences

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