Article
Analysis of TPOX short tandem repeat locus with matrix-associated laser desorption/ionization time-of-flight-based restriction fragment mass polymorphism assay.
Analytical biochemistry - 1 May 2011
Cha Yoon Seok, Choi Suh Hee, Lee Joo-Hyoung, Shin Soo-Kyung, Lee Seung Hwan, Lee Soong Deok, Kim Soo-Ok, Hong Sun Pyo
Abstract excerpt
Short tandem repeat (STR) loci are routinely analyzed by capillary electrophoresis. However, this method has several disadvantages, including long operational time, low throughput, and inaccuracy. As a result of the introduction of matrix-associated laser desorption/ionization time-of-flight (MALDI-TOF) and electrospray ionization (ESI), mass spectrometry has become an alternative method for genotyping...
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