Article
Reduced neuronal activity and reactivation in Alzheimer's disease.
Progress in brain research - 1 Jan 1998
Swaab D F, Lucassen P J, Salehi A, Scherder E J, van Someren E J, Verwer R W
Abstract excerpt
1. Alzheimer's disease is a multifactorial disease in which age and APOE-epsilon 4 are important risk factors. Various mutations and even viral infections such as herpes simplex (Itzhaki et al., 1997) may play an additional role. 2. The neuropathological hallmarks of Alzheimer's disease (AD), i.e. amorphous plaques, neuritic plaques (NPs), pretangles, neurofibrillary tangles (NFT) and cell death are not part of a...
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