Reduced neuronal activity and reactivation in Alzheimer's disease.

doi:10.1016/s0079-6123(08)64027-3

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Article

Reduced neuronal activity and reactivation in Alzheimer's disease.

Progress in brain research - 1 Jan 1998

Swaab D F, Lucassen P J, Salehi A, Scherder E J, van Someren E J, Verwer R W

Abstract excerpt

1. Alzheimer's disease is a multifactorial disease in which age and APOE-epsilon 4 are important risk factors. Various mutations and even viral infections such as herpes simplex (Itzhaki et al., 1997) may play an additional role. 2. The neuropathological hallmarks of Alzheimer's disease (AD), i.e...

Topics

Aging
Alzheimer Disease
Animals
Apolipoprotein E4
Apolipoproteins E
Brain
Humans
Models, Neurological
Mutation
Neurofibrillary Tangles
Neurons

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