Article
[Molecular bases of the programmed cell death process: implications of tumor suppressor protein p53 and other proteins in the control of cell cycle. Mechanisms of apoptotic action. Review].
Investigacion clinica - 1 Dec 1998
Merino J J, Cordero-Campaña M I
Abstract excerpt
Apoptosis is a mechanism of cell death that occurs in normal development and on the regulation of vertebrate tissues and organ cellularity. Neurons undergo p53-dependent and p53-independent apoptosis, depending upon the stimulus that triggers DNA fragmentation. Many neurons in the developing nerv...
Topics
- Animals
- Apoptosis
- Cell Cycle
- Cell Death
- Colorectal Neoplasms
- Cysteine Endopeptidases
- Cytoskeleton
- Genes, myc
- Genes, p53
- Humans
- Mice
- Mutation
- Proto-Oncogene Proteins c-bcl-2
- Retinoblastoma Protein
- Transcription, Genetic
- Transcriptional Activation