A comparison of power to detect a QTL in sib-pair data using multivariate phenotypes, mean phenotypes, and factor scores.

doi:10.1023/a:1021665501312

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Article

A comparison of power to detect a QTL in sib-pair data using multivariate phenotypes, mean phenotypes, and factor scores.

Behavior genetics - 1 Sept 1998

Boomsma D I, Dolan C V

Abstract excerpt

The power to detect a quantitative trait locus (QTL) in sib-pair data is investigated. We assume that we have at our disposal 3 or 4 related phenotypic measures in a sample of sib-pairs. Individual differences in these phenotypes are due to a common QTL and specific (i.e., unique to each phenotyp...

Topics

Chi-Square Distribution
Chromosome Mapping
Humans
Models, Genetic
Multivariate Analysis
Phenotype
Quantitative Trait, Heritable
Social Environment

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