Article
Genetic variation and susceptibilities to protease inhibitors among subtype B and F isolates in Brazil.
Antimicrobial agents and chemotherapy - 1 Feb 1999
Tanuri A, Vicente A C, Otsuki K, Ramos C A, Ferreira O C, Schechter M, Janini L M, Pieniazek D, Rayfield M A
Abstract excerpt
The genetic variation of the human immunodeficiency virus type 1 (HIV-1) protease gene (prt) permits the classification of HIV-1 strains into five distinct protease subtypes, which follow the gag subtyping patterns. The susceptibilities of non-B-subtype strains to protease inhibitors (PIs) and ot...
Topics
- Amino Acid Sequence
- Anti-HIV Agents
- Brazil
- DNA, Viral
- Genetic Variation
- Genotype
- HIV Infections
- HIV Protease
- HIV Protease Inhibitors
- HIV-1
- Humans
- Indinavir
- Microbial Sensitivity Tests
- Molecular Sequence Data
- Phylogeny
- Saquinavir
- Sequence Homology, Amino Acid