Article
The human vasoactive intestinal Peptide/Pituitary adenylate cyclase activating peptide receptor 1 (VPAC1): constitutive activation by mutations at threonine 343.
Biochemical and biophysical research communications - 8 Jan 1999
Gaudin P, Couvineau A, Rouyer-Fessard C, Maoret J J, Laburthe M
Abstract excerpt
The human vasoactive intestinal peptide/pituitary adenylate cyclase activating peptide receptor1 (VPAC1) belongs to the class II subfamily of G protein-coupled receptors. Specific changes by mutagenesis of a strictly conserved threonine (H) into lysine (K), proline (P) or alanine (A) at position...
Topics
- Animals
- COS Cells
- Humans
- Mutagenesis, Site-Directed
- Mutation
- Receptors, Vasoactive Intestinal Peptide
- Signal Transduction
- Threonine
- Transfection
- Vasoactive Intestinal Peptide