Article
Strategies for mutational analysis of the large multiexon ATM gene using high-density oligonucleotide arrays.
Genome research - 1 Dec 1998
Hacia J G, Sun B, Hunt N, Edgemon K, Mosbrook D, Robbins C, Fodor S P, Tagle D A, Collins F S
Abstract excerpt
Mutational analysis of large genes with complex genomic structures plays an important role in medical genetics. Technical limitations associated with current mutation screening protocols have placed increased emphasis on the development of new technologies to simplify these procedures. High-densi...
Topics
- Ataxia Telangiectasia Mutated Proteins
- Cell Cycle Proteins
- DNA Mutational Analysis
- DNA-Binding Proteins
- Exons
- Female
- Human Genome Project
- Humans
- Leucine Zippers
- Male
- Mutation
- Oligonucleotide Array Sequence Analysis
- Phosphatidylinositol 3-Kinases
- Protein Serine-Threonine Kinases