Article
Angiotensin-converting enzyme and angiotensin II receptor 1 polymorphisms: association with early coronary disease.
Cardiovascular research - 1 Nov 1998
Alvarez R, Reguero J R, Batalla A, Iglesias-Cubero G, Cortina A, Alvarez V, Coto E
Abstract excerpt
OBJECTIVE: To examine the association between coronary artery disease and polymorphisms at the angiotensin-converting enzyme (ACE) and angiotensin II type 1 receptor (AT1R) genes. METHODS: A total of 181 patients younger than 50 years and 240 controls from the same homogeneous Caucasian population (Asturias, Northern Spain) were genotyped (using polymerase chain reaction) for the ACE insertion/deletion (ACE-I/D)...
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