Article
Renin-angiotensin system gene polymorphisms and premature coronary heart disease.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Mar 2005
Sekuri Cevad, Cam F Sirri, Ercan Ertugrul, Tengiz Istemihan, Sagcan Abdi, Eser Erhan, Berdeli Afig, Akin Mustafa
Abstract excerpt
INTRODUCTION: Experimental and clinical studies demonstrated that the renin-angiotensin system (RAS) affects the pathogenesis of atherosclerosis and prognosis of coronary heart disease (CHD). The aim of this study was to investigate the genotype distribution and the allele frequencies of three RAS genes polymorphisms and their effects on premature CHD in a Turkish population. MATERIALS AND METHODS: One-hundred...
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