Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Angiotensin-converting enzyme single nucleotide polymorphism is a genetic risk factor for cardiovascular disease: a cohort study of hypertensive patients.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jun 2011

Kato Nozomi, Tatara Yuji, Ohishi Mitsuru, Takeya Yasushi, Onishi Miyuki, Maekawa Yoshihiro, Rakugi Hiromi

Abstract excerpt

The renin-angiotensin system (RAS) adversely affects stroke and cardiovascular disease; polymorphisms in genes involved in this system are associated with cardiovascular disease. The aim of the present study was to confirm the genetic risk of these polymorphisms for stroke and cardiovascular events in a cohort study of 515 hypertensive patients in Japan (follow-up period 90.6±30.2 months). The insertion/deletion...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Cardiovascular Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Hypertension

Share to Kaplan-Meier Estimate

Share to Peptidyl-Dipeptidase A

Share to Proportional Hazards Models

Share to Risk Factors

Source

Identifiers

PMID: 21412245
DOI: 10.1038/hr.2011.28

Genes

ACE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Angiotensin-converting enzyme single nucleotide polymorphism is a genetic risk factor for cardiovascular disease: a cohort study of hypertensive patients.PMID 21412245Read ↗

Association between angiotensin-converting enzyme insertion/deletion polymorphisms and the risk of heart disease: an updated meta-analysis.Semantic proximity Read ↗

Association between the ACE I/D polymorphism and risk of ischemic stroke: an updated meta-analysis of 47,026 subjects from 105 case-control studies.Semantic proximity Read ↗

Does angiotensin-converting enzyme gene polymorphism affect blood pressure? Findings after 6 years of follow-up in healthy subjects.Semantic proximity Read ↗

Associations between antihypertensive drug-related gene polymorphisms and cardiovascular outcomes in hypertensive patients: a gene-drug interaction study.Semantic proximity Read ↗

Angiotensin-converting enzyme gene I/D polymorphism increases the susceptibility to hypertension and additive diseases: A study on North Indian patientsSemantic proximity Read ↗

[ACE gene polymorphism and cardiovascular diseases].Semantic proximity Read ↗

Angiotensin-converting enzyme insertion/deletion polymorphism and risk of myocardial infarction in an updated meta-analysis based on 34993 participants.Semantic proximity Read ↗

Angiotensin I-converting enzyme gene polymorphism enhances the effect of hypercholesterolemia on the risk of coronary heart disease in a general Japanese population: the hisayama study.Semantic proximity Read ↗

[The effect of the angiotensinogen M235T and the angiotensin-converting enzyme I/D polymorphisms on arterial hypertension and other cardiovascular risk factors].Semantic proximity Read ↗

Cardiovascular diseases and molecular variants of the renin-angiotensin system components in Slovak population.Semantic proximity Read ↗

Renin–angiotensin system gene polymorphisms: potential mechanisms for their association with cardiovascular diseasesSemantic proximity Read ↗

Genetic variation in the renin-angiotensin-aldosterone system is associated with cardiovascular risk factors and early mortality in established coronary heart disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.