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Article

Detection of the t(2;5)‐associated NPM/ALK fusion cDNA in peripheral blood cells of healthy individuals

1 Dec 1998

Abstract excerpt

The translocation t(2;5), which leads to the fusion of the nucleophosmin gene (NPM) on chromosome 5q35 to the receptor kinase ALK on chromosome 2p23, is found in CD30+ anaplastic large cell lymphomas and some cases of B-cell lymphoma. Hodgkin's disease (HD) is a malignant lymphoma characterized by large multinucleated tumour cells, Hodgkin and Reed-Sternberg (H&RS) cells, surrounded by a dense lymphohistiocytic...

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Identifiers

PMID: 9886332
DOI: 10.1046/j.1365-2141.1998.01097.x

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Detection of the t(2;5)‐associated NPM/ALK fusion cDNA in peripheral blood cells of healthy individualsPMID 9886332Read ↗

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