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Article

Isolation of 48 genetic markers appropriate for high throughput genotyping of inbred rat strains by B1 repetitive sequence-representational difference analysis.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 1998

Ushijima T, Nomoto T, Sugimura T, Housman D E, Nagao M

Abstract excerpt

Mapping of genetic suppressors, modifiers, and quantitative trait loci (QTLs) requires genetic markers that can be efficiently and inexpensively genotyped for a large number of individuals. To isolate rat genetic markers suitable for this purpose, representational difference analysis (RDA) was performed with amplicons prepared by PCR with the B1 repetitive sequence used as the primer (B1-amplicons). In total, 48...

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PMID: 9880669
DOI: 10.1007/s003359900916

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