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Article

Biometrical genetic analysis of ethanol's psychomotor stimulant effect.

Alcoholism, clinical and experimental research - 1 Aug 1994

Dudek B C, Tritto T

Abstract excerpt

Hereditary influences on psychomotor stimulant effects of ethanol (ETOH) were studied in a classical Mendelian cross of DBA/2Abg (D2) and C57BL/6Abg (B6) inbred mouse strains. A dose-response study with nine doses (0-3.5 g/kg ip) indicated that B6 mice lack the activational limb of the biphasic curve (< or = 1.5 g/kg), as assessed in a 15-min test. D2 mice ran greater distances and ran faster, at doses up to 2.5...

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Source

Identifiers

PMID: 7978110
DOI: 10.1111/j.1530-0277.1994.tb00066.x

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