Article
Polysialic acid facilitates migration of luteinizing hormone-releasing hormone neurons on vomeronasal axons.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Jan 1999
Yoshida K, Rutishauser U, Crandall J E, Schwarting G A
Abstract excerpt
Luteinizing hormone-releasing hormone (LHRH) neurons migrate from the olfactory placode to the forebrain in association with vomeronasal nerves (VNN) that express the polysialic acid-rich form of the neural cell adhesion molecule (PSA-NCAM). Two approaches were used to investigate the role of PSA...
Topics
- Animals
- Axons
- Cell Movement
- Electrophoresis, Polyacrylamide Gel
- Glycoside Hydrolases
- Gonadotropin-Releasing Hormone
- Immunoblotting
- Immunohistochemistry
- Mice
- Mutation
- Neural Cell Adhesion Molecules
- Neural Pathways
- Neurons
- Sialic Acids
- Vomeronasal Organ