Article
The role of polysialic acid in migration of olfactory bulb interneuron precursors in the subventricular zone.
Neuron - 1 Apr 1996
Hu H, Tomasiewicz H, Magnuson T, Rutishauser U
Abstract excerpt
Transplantation studies have been used to show that tangential migration of olfactory bulb interneuron precursors is retarded in NCAM-mutant mice, and that this defect reflects loss of NCAM polysialic acid (PSA). In contrast, radial migration of cells within the bulb did not require PSA. Reciprocal transplantations between wild-type and mutant mice have revealed that the mutation affects the in vivo migration...
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