Article
The role of polysialic acid in migration of olfactory bulb interneuron precursors in the subventricular zone.
Neuron - 1 Apr 1996
Hu H, Tomasiewicz H, Magnuson T, Rutishauser U
Abstract excerpt
Transplantation studies have been used to show that tangential migration of olfactory bulb interneuron precursors is retarded in NCAM-mutant mice, and that this defect reflects loss of NCAM polysialic acid (PSA). In contrast, radial migration of cells within the bulb did not require PSA. Reciproc...
Topics
- Animals
- Animals, Newborn
- Brain
- Cell Movement
- Collagen
- Culture Media
- Culture Techniques
- Fluorescent Antibody Technique, Indirect
- Interneurons
- Mice
- Mice, Mutant Strains
- Mutation
- Neural Cell Adhesion Molecules
- Olfactory Bulb
- Sialic Acids
- Stem Cells