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Article

The STAR protein, GLD-1, is a translational regulator of sexual identity in Caenorhabditis elegans.

The EMBO journal - 4 Jan 1999

Jan E, Motzny C K, Graves L E, Goodwin E B

Abstract excerpt

The Caenorhabditis elegans sex determination gene, tra-2, is translationally regulated by elements in the 3'-untranslated region called TGEs. TGEs govern the translation of mRNAs in both invertebrates and vertebrates, indicating that this is a highly conserved mechanism for controlling gene activity. A factor called DRF, found in worm extracts binds the TGEs and may be a repressor of translation. Using the yeast...

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Identifiers

PMID: 9878068
DOI: 10.1093/emboj/18.1.258
PMCID: PMC1171120

Genes

TRA

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Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The STAR protein, GLD-1, is a translational regulator of sexual identity in Caenorhabditis elegans.PMID 9878068Read ↗

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Translational regulation of tra-2 by its 3' untranslated region controls sexual identity in C. elegans.Semantic proximity Read ↗

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