Article
Immunogenetic basis of environmental lung disease: lessons from the berylliosis model.
The European respiratory journal - 1 Dec 1998
Saltini C, Amicosante M, Franchi A, Lombardi G, Richeldi L
Abstract excerpt
The role of genetic factors has been hypothesized in the pathogenesis of a number of chronic inflammatory lung diseases. The genes of the major histocompatibility complex (MHC) locus on human chromosome 6 have been identified as important determinants in diseases caused both by inorganic and organic compounds such as beryllium, gold, acid anhydrides, isocyanates and grass pollens. Since many environmental factors...
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