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Article

<i>NOEY2</i> (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas

5 Jan 1999

Abstract excerpt

Using differential display PCR, we have identified a gene [NOEY2, ARHI (designation by the Human Gene Nomenclature Committee)] with high homology to ras and rap that is expressed consistently in normal ovarian and breast epithelial cells but not in ovarian and breast cancers. Reexpression of NOEY2 through transfection suppresses clonogenic growth of breast and ovarian cancer cells. Growth suppression was...

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PMID: 9874798
DOI: 10.1073/pnas.96.1.214

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