Article
Increase in quinolone resistance in a Haemophilus influenzae strain isolated from a patient with recurrent respiratory infections treated with ofloxacin.
Antimicrobial agents and chemotherapy - 1 Jan 1999
Vila J, Ruiz J, Sanchez F, Navarro F, Mirelis B, de Anta M T, Prats G
Abstract excerpt
The increase in the level of quinolone resistance of Haemophilus influenzae clinical isolates during ofloxacin therapy of a patient with recurrent respiratory infections was investigated. The first isolate (MIC of ciprofloxacin of 2 microg/ml) and the second isolate (MIC of 32 microg/ml) belonged...
Topics
- Amino Acid Substitution
- Anti-Infective Agents
- DNA Topoisomerase IV
- DNA Topoisomerases, Type II
- Female
- Haemophilus Infections
- Haemophilus influenzae
- Humans
- Microbial Sensitivity Tests
- Middle Aged
- Mutation
- Ofloxacin
- Polymerase Chain Reaction
- Recurrence