Article
Vacuolating toxin gene polymorphism among Helicobacter pylori clinical isolates and its association with m1, m2, or chimeric vacA middle types.
Scandinavian journal of gastroenterology - 1 Nov 1998
Yang J C, Kuo C H, Wang H J, Wang T C, Chang C S, Wang W C
Abstract excerpt
BACKGROUND: Helicobacter pylori vacuolating cytotoxin encoded by vacA plays an essential role in H. pylori-related pathogenesis. Specific vacA alleles are believed to be associated with increased virulence. Association among vacA polymorphism, vacA middle genotypes, and various H. pylori-related...
Topics
- Bacterial Proteins
- Cytotoxins
- Female
- Gastrointestinal Diseases
- Genetic Variation
- Genotype
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Male
- Middle Aged
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length