Article
Mannose-binding protein in HIV-seropositive patients does not contribute to disease progression or bacterial infections.
International journal of STD & AIDS - 1 Nov 1998
McBride M O, Fischer P B, Sumiya M, McClure M O, Turner M W, Skinner C J, Weber J N, Summerfield J A
Abstract excerpt
This study set out to investigate whether plasma mannose-binding protein (MBP) deficiency caused by mutations in the MBP gene associates with pyogenic or opportunistic infections in HIV-infected patients. Plasma samples were selected randomly from 131 HIV-infected patients followed prospectively...
Topics
- AIDS-Related Opportunistic Infections
- Bacterial Infections
- Blotting, Southern
- Carrier Proteins
- Chi-Square Distribution
- Disease Progression
- Enzyme-Linked Immunosorbent Assay
- Genotype
- Humans
- Mannose
- Mutation
- Polymerase Chain Reaction
- Prospective Studies
- Statistics, Nonparametric