Article
Mannose-binding protein in HIV-seropositive patients does not contribute to disease progression or bacterial infections.
International journal of STD & AIDS - 1 Nov 1998
McBride M O, Fischer P B, Sumiya M, McClure M O, Turner M W, Skinner C J, Weber J N, Summerfield J A
Abstract excerpt
This study set out to investigate whether plasma mannose-binding protein (MBP) deficiency caused by mutations in the MBP gene associates with pyogenic or opportunistic infections in HIV-infected patients. Plasma samples were selected randomly from 131 HIV-infected patients followed prospectively for a period not exceeding 12 months or until death. Plasma MBP concentrations were measured by an ELISA and genotyping...
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