Antibody recognition of epitopes on wild-type and mutant beta-(1-->4)-galactosyltransferase-1.

doi:10.1016/s0008-6215(98)00247-x

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Article

Antibody recognition of epitopes on wild-type and mutant beta-(1-->4)-galactosyltransferase-1.

Carbohydrate research - 1 Nov 1998

Keusch J, Panayotou G, Malissard M, Berger E G, Appert H E, Lydyard P M, Delves P J

Abstract excerpt

The epitopes present on beta-(1-->4)-galactosyltransferase-1 (beta 4Gal-T1) have been explored using a panel of monoclonal antibodies (mAbs) raised against the soluble form of the human enzyme. Reactivity of the antibodies with site-specific and truncated mutants of human beta 4Gal-T1 suggests th...

Topics

Antibodies, Monoclonal
Catalysis
Epitope Mapping
Humans
Mutation
N-Acetyllactosamine Synthase
beta-N-Acetylglucosaminylglycopeptide beta-1,4-Galactosyltransferase

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