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Article

Antibody recognition of epitopes on wild-type and mutant beta-(1-->4)-galactosyltransferase-1.

Carbohydrate research - 1 Nov 1998

Keusch J, Panayotou G, Malissard M, Berger E G, Appert H E, Lydyard P M, Delves P J

Abstract excerpt

The epitopes present on beta-(1-->4)-galactosyltransferase-1 (beta 4Gal-T1) have been explored using a panel of monoclonal antibodies (mAbs) raised against the soluble form of the human enzyme. Reactivity of the antibodies with site-specific and truncated mutants of human beta 4Gal-T1 suggests the presence of a major immunogenic epitope cluster consisting of four epitopes within the stem region and mapping...

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Identifiers

PMID: 9861700
DOI: 10.1016/s0008-6215(98)00247-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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