Article
Crm1p mediates regulated nuclear export of a yeast AP-1-like transcription factor.
The EMBO journal - 15 Dec 1998
Yan C, Lee L H, Davis L I
Abstract excerpt
The yeast AP-1-like transcription factor, Yap1p, activates genes required for the response to oxidative stress. Yap1p is normally cytoplasmic and inactive, but will activate by nuclear translocation if cells are placed in an oxidative environment. Here we show that Yap1p is a target of the beta-k...
Topics
- Amino Acid Sequence
- Biological Transport
- Carrier Proteins
- Cell Compartmentation
- Cell Nucleus
- Cytoplasm
- DNA-Binding Proteins
- Guanosine Triphosphate
- Immunoblotting
- Karyopherins
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Oxidation-Reduction
- Precipitin Tests
- Protein Binding
- Receptors, Cytoplasmic and Nuclear
- Saccharomyces cerevisiae Proteins