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Article

Identification of structural elements involved in the interaction of simian virus 40 small tumor antigen with protein phosphatase 2A.

The Journal of biological chemistry - 25 Dec 1998

Mateer S C, Fedorov S A, Mumby M C

Abstract excerpt

SV40 small tumor antigen (small-t) was used as a model to identify structural elements involved in the interactions between regulatory proteins and protein phosphatase 2A (PP2A). Using mutant proteins and synthetic peptides, we identified a small domain within small-t that is a major site for interaction with the dimeric form of PP2A. A series of small-t truncation mutants identified a region surrounding the...

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PMID: 9857076
DOI: 10.1074/jbc.273.52.35339

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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