Article
Binding specificity of protein phosphatase 2A core enzyme for regulatory B subunits and T antigens.
Journal of virology - 1 Jan 1999
Ruediger R, Fields K, Walter G
Abstract excerpt
The core enzyme of protein phosphatase 2A is composed of a regulatory subunit A and a catalytic subunit C. It is controlled by three types of regulatory B subunits (B, B', and B") and by tumor (T) antigens, which are unrelated by sequence but bind to overlapping regions on the A subunit. To find out whether the different B subunits and T antigens bind to identical or distinct amino acids of the A subunit, mutants...
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