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Article

Increased cardiac norepinephrine release in spontaneously hypertensive rats: role of presynaptic alpha-2A adrenoceptors.

Journal of hypertension - 1 Jul 2003

Zugck Christian, Lossnitzer Dirk, Backs Johannes, Kristen Arnt, Kinscherf Ralf, Haass Markus

Abstract excerpt

OBJECTIVES AND DESIGN: An increased sympathoadrenergic activation is thought to contribute to the maintenance of elevated blood pressure levels in hypertension. Therefore, the regulation of cardiac presynaptic sympathetic neurotransmission was investigated in spontaneously hypertensive (SHR) and Wistar-Kyoto rats (WKY). METHODS AND RESULTS: Electrical field stimulation (1 min, 4 Hz) evoked a higher norepinephrine...

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PMID: 12817185
DOI: 10.1097/00004872-200307000-00026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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