Article
Replication properties of clade A/C chimeric feline immunodeficiency viruses and evaluation of infection kinetics in the domestic cat.
Journal of virology - 1 Aug 2008
de Rozìeres Sohela, Thompson Jesse, Sundstrom Magnus, Gruber Julia, Stump Debora S, de Parseval Aymeric P, VandeWoude Sue, Elder John H
Abstract excerpt
Feline immunodeficiency virus (FIV) causes progressive immunodeficiency in domestic cats, with clinical course dependent on virus strain. For example, clade A FIV-PPR is predominantly neurotropic and causes a mild disease in the periphery, whereas clade C FIV-C36 causes fulminant disease with CD4(+) T-cell depletion and neutropenia but no significant pathology in the central nervous system. In order to map...
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